Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma

doi:10.21873/invivo.12353

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23409

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23409

Title:	Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma
Authors:	Lai, GS;Li, JR;Wang, SS;Chen, CS;Yang, CK;Hung, SC;Cheng, CL;Ou, YC;Chiu, KY
Keywords:	Key Words;Fat invasion;pathological T3a;prognosis;renal cell carcinoma;renal vein invasion
Date:	2021
Issue Date:	2022-08-05T09:36:49Z (UTC)
Publisher:	INT INST ANTICANCER RESEARCH
ISSN:	0258-851X
Abstract:	Background/Aim: To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. Patients and Methods: We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution. Results: At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.103.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048). Conclusion: For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI.
URI:	http://dx.doi.org/10.21873/invivo.12353 https://www.webofscience.com/wos/woscc/full-record/WOS:000648906100019 https://ir.csmu.edu.tw:8080/handle/310902500/23409
Relation:	IN VIVO ,2021,v35,issue 2, P1083-1089
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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