中山醫學大學機構典藏 CSMUIR:Item 310902500/23338
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    题名: �w�M�P�X�����G Human amniotic membrane grafts for retinal breaks in diabetic tractional retinal detachment and combined tractional and rhegmatogenous retinal detachment (Retracted article. See vol. 12, 2022)
    作者: Chen, YC;Chen, SN
    日期: 2021
    上传时间: 2022-08-05T09:35:40Z (UTC)
    出版者: NATURE PORTFOLIO
    ISSN: 2045-2322
    摘要: To describe the surgical outcomes of using human amniotic membrane (hAM) grafts in the management of retinal breaks in diabetic tractional detachment (TRD) and combined tractional and rhegmatogenous retinal detachment (CTRRD). A retrospective case series of 10 eyes with TRD or CTRRD receiving pars plana vitrectomy with hAM grafts implantation, compared with 13 controls receiving the same surgery without hAM grafts. Best-corrected visual acuity (BCVA) and re-detachment rate were compared between two groups. Postoperatively, all eyes in the hAM group had retina attachment without recurrence, while 9 eyes in the control group had retina re-detachment and required additional surgery (0% vs 69.2%, p=0.003). The BCVA significantly improved in the hAM group (from 1.96 +/- 0.95 to 1.44 +/- 0.77 in log MAR, p=0.03), but not improved in control group (p=0.20). Postoperative optical coherence tomography of the eyes receiving hAM grafts demonstrated glial tissue regeneration and restoration of ellipsoid zone. In diabetic TRD or CTRRD, hAM grafts could be an effective method, with promising outcome. Compared to standard surgery, it could result in higher retina reattachment rate and significant visual improvement. Moreover, it may offer the adjunctive benefit in tissue regeneration and fasten ellipsoid zone restoration.
    URI: http://dx.doi.org/10.1038/s41598-021-86804-z
    https://www.webofscience.com/wos/woscc/full-record/WOS:000640611400020
    https://ir.csmu.edu.tw:8080/handle/310902500/23338
    關聯: SCIENTIFIC REPORTS ,2021,v11,issue 1
    显示于类别:[中山醫學大學研究成果] 期刊論文

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