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    Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/22983


    Title: 探究白念珠菌中DNA複製起始者DDK如何因應環境信號和基因毒性控制形態發生
    Authors: 謝家慶
    Contributors: 中山醫學大學生物醫學科學學系(所)
    Keywords: 白色念珠菌;Dbf4依賴的Cdc7激?;形態發生;致病力;環境信號;基因毒性壓力
    Candida albicans;Dbf4-dependent kinase;morphogenesis;virulence;environmental cues;genotoxic stress
    Date: 2019-07-01
    Issue Date: 2022-07-28T02:45:24Z (UTC)
    Abstract: 計畫名稱:探究白念珠菌中DNA複製起始者DDK如何因應環境信號和基因毒性控制形態發生
    成果報告:
    執行起迄:2019/08/01~2021/01/31
    總核定金額:1,410,000元?(各年度經費明細)
    計畫概述:白色念珠菌乃人類伺機性真菌病菌,是院內感染高致死率主因,治療極耗醫療資源但成效不彰。其形態發生與致病力有高關聯故為研究主軸。此菌Dbf4依賴的Cdc7激?(CaDDK)能啟動DNA複製具演化上...(詳)
    中文摘要:我們的目標是揭示調節念珠菌介導的CaDDK介導的形態發生的機制,並提出為期三年的項目以驗證該假設。有三個具體目標:(1)驗證CaDDK是否已整合到已知的酵母菌-菌絲過渡(YHT)網絡中;(2)...(詳)
    英文摘要:Our goal is to unravel the mechanisms that regulate morphogenesis mediated by CaDDK in Candida albicans and propose a three-year project to validate the hypothesis. There are three specific aims: ...(詳)
    URI: https://ir.csmu.edu.tw:8080/handle/310902500/22983
    Appears in Collections:[專題研究計畫(教師)] 教師研究計畫

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