中山醫學大學機構典藏 CSMUIR:Item 310902500/22887
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    CSMUIR > Thematic Research Project > Research Project >  Item 310902500/22887
    Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/22887


    Title: 探討N-乙?半胱氨酸降低舒疼誘導急性肝損傷小鼠的劑量效應與合併類黃酮輔助治療的可能機制
    Authors: 王淑紅
    Contributors: 中山醫學大學生物醫學科學學系(所)
    Keywords: 乙醯胺基苯酚;舒疼;藥物誘導急性肝損傷;N-乙?半胱氨酸;類黃酮;發炎因子;抗氧化;抗細胞凋亡。
    N-acetyl-p-aminophenol (APAP);Propacetamol;Drug-induced acute liver damage;N-acetyl cysteine (NAC);Flavonoids;pro-inflammatory factors;anti-inflammation;anti-apoptosis
    Date: 2019-07-01
    Issue Date: 2022-07-28T02:44:08Z (UTC)
    Abstract: 計畫名稱:探討N-乙?半胱氨酸降低舒疼誘導急性肝損傷小鼠的劑量效應與合併類黃酮輔助治療的可能機制
    成果報告:
    執行起迄:2019/08/01~2020/07/31
    總核定金額:930,000元?(各年度經費明細)
    計畫概述:NAC是臨床上APAP中毒的治療用藥,本研究探討NAC劑量與治療時間對於APAP中毒小鼠肝臟再生的影響,將可以提供臨床上病人最適合的NAC劑量與治療時間的參考。探討類黃酮輔助NAC治療的可行性...(詳)
    中文摘要:乙醯胺基苯酚(N-acetyl-p-aminophenol, APAP)是最常用的解熱鎮痛藥物之一,過量的APAP會引起人體和實驗動物的肝毒性及腎毒性,甚至導致死亡。臨床上N-乙?半胱氨酸(N...(詳)
    英文摘要:N-acetyl-p-aminophenol (APAP) is one of the most commonly used antipyretic analgesics. Excess APAP causes liver toxicity and nephrotoxicity in both humans and laboratory animals, and even lead to ...(詳)
    URI: https://ir.csmu.edu.tw:8080/handle/310902500/22887
    Appears in Collections:[Thematic Research Project] Research Project

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