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https://ir.csmu.edu.tw:8080/ir/handle/310902500/22465
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| Title: | Impact of Obesity on a Chinese Population with Erosive Esophagitis and Barrett's Esophagus |
| Authors: | Lee, Shou-Wu;Lien, Han-Chung;Lee, Teng-Yu;Tung, Chun-Fang;Yeh, Hong-Zen;Chang, Chi-Sen |
| Keywords: | Barrett esophagus;Gastroesophageal reflux;Obesity |
| Date: | 2017-05-15 |
| Issue Date: | 2022-06-28T01:37:42Z (UTC)
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| Publisher: | Gut and Liver |
| Abstract: | Background/aims: The aim of this study was to investigate the associations between obesity and erosive esophagitis (EE) or Barrett's esophagus (BE) in a Chinese population.
Methods: Data from subjects were retrospectively collected from 2006 to 2009. Individuals with BE were identified and age- and sex-matched at a 1:2 ratio with normal esophagocardial junction and EE patients. The subjects were stratified into two groups: the normal weight group and overweight/ obesity group (body mass index ≥25 mg/m²) or the normal waist group and abdominal obesity group (waist circumference ≥90 cm for men and ≥80 cm for women).
Results: Overall, 45%, 72%, and 52% were overweight/obese and 23%, 65%, and 18% had abdominal obesity in the normal, EE, and BE groups, respectively. Positive associations were identified between EE and overweight/obesity (odds ratio [OR], 3.14; 95% confidence interval [CI], 1.75 to 5.66) and abdominal obesity (OR, 6.22; 95% CI, 3.34 to 11.57); however, the associations were nonsignificant between BE and overweight/obesity (OR, 1.32; 95% CI, 0.67 to 2.61) or abdominal obesity (OR, 0.73; 95% CI, 0.31 to 1.73). Female BE patients had a significantly increased rate of being overweight/obese.
Conclusions: Obesity is a contributing factor in EE. The association of BE and obesity was not significant, with the exception of female BE cases. |
| URI: | https://ir.csmu.edu.tw:8080/handle/310902500/22465 |
| Relation: | Gut Liver, 11(3), 377-382. |
| Appears in Collections: | [醫學系] 期刊論文
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| gnl-11-377.pdf | | 247Kb | Adobe PDF | 77 | View/Open |
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