Obesity control via carnitine drink in obese adults: A randomized, double-blind placebo-controlled human trial

中山醫學大學機構典藏 CSMUIR > 行政單位 > 研發處 > 期刊論文 > Item 310902500/21817

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/21817

Title:	Obesity control via carnitine drink in obese adults: A randomized, double-blind placebo-controlled human trial
Authors:	Chien-Chun Li ； Chun-Ting Liu ； Shih-Chuan Liu ； Ching-Pin Lin ； Yi-Ching Li ； You-Cheng Shen
Contributors:	中山醫學大學
Keywords:	exercise prescriptions ； frailty ； heart rate reserve ； intervention effects ； Rating of Perceived Exertion
Date:	2019-06-01
Issue Date:	2021-10-04T02:55:17Z (UTC)
Publisher:	研發處育成中心暨產學合作組
Abstract:	Background and Purpose: A randomized, double-blind, placebo-controlled human trial was conducted to investigate the effects of carnitine drink on obesity in obese subjects in Taiwan. Methods: Fifty subjects with simple obesity and body mass index (BMI)≧27 (or ＞30% body fat) who engaged in aerobic exercise for 2-4h weekly were recruited. The subjects were randomly assigned to receive either carnitine drink or placebo, once daily, for 6 consecutive weeks. Body weight, body fat, and biochemical indicators (i.e., blood glucose, blood lipids, albumin, serum creatinine, blood urea nitrogen, glutamic oxalacetic transaminase (GOT), and glutamic-pyruvate transaminase (GPT)) were measured every 3 weeks. Subsequently, magnetic resonance imaging was conducted to examine the distribution and thickness of abdominal fat and the results were used to determine the effects of carnitine drink on body fat. Results: A total of 28 subjects completed the study. Six weeks of consumption of carnitine drink led to 0.7% and 2.1 kg reductions in body fat and body weight, respectively, compared with the placebo group. In addition, cholesterol level was reduced by 3.8%. No severe adverse effects were observed. Conclusions: Intake of carnitine drink is effective for reducing body weight and cholesterol in obese subjects.
URI:	https://ir.csmu.edu.tw:8080/handle/310902500/21817
Relation:	中山醫學雜誌, 30卷1期, P47 - 54
Appears in Collections:	[研發處] 期刊論文

Files in This Item:

File	Description	Size	Format
Obesity control via carnitine drink in obese adults A randomized, double-blind placebo-controlled hu.pdf		1358Kb	Adobe PDF	279	View/Open

View Licence

Loading...