Idiopathic hyperammonemic encephalopathy after chemotherapy in a patient with rectal cancer

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题名:	Idiopathic hyperammonemic encephalopathy after chemotherapy in a patient with rectal cancer
作者:	Jui-Hung Chen ； Pei Lin ； Hsin-Hsin Huang ； Chien-Han Tsao
贡献者:	中山醫學大學
关键词:	Idiopathic hyperammonemic encephalopathy ； Hepatic insufficiency ； 5-Fluorouracil
日期:	2021-06-01
上传时间:	2021-09-13T02:34:01Z (UTC)
出版者:	研發處育成中心暨產學合作組
摘要:	Idiopathic hyperammonemic encephalopathy is a rare complication of chemotherapy that has been described in patients with hematological malignancy, colon cancer, and hepatocellular carcinoma in the presence of noncirrhotic liver. The cause of this syndrome, which can be fatal, is not well understood. We present a case of rectal cancer without underlying liver dysfunction who suffered abrupt alteration in mental status after the first course of chemotherapy. Ammonia-lowering therapy was started immediately, without cessation of chemotherapy. For additional courses of chemotherapy, reduction to 75% of normal dosage was found to be safe and to produce satisfactory results.
URI:	https://ir.csmu.edu.tw:8080/handle/310902500/21763
關聯:	中山醫學雜誌 , 32卷1期, P101 - 103
显示于类别:	[研發處] 期刊論文

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