中山醫學大學機構典藏 CSMUIR:Item 310902500/21014
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    题名: High agatston calcium score of intracranial carotid artery: A significant risk factor for cognitive impairment
    作者: Kao, Hung-Wen
    Liou, Michelle
    Chung, Hsiao-Wen
    Liu, Hua-Shan
    Tsai, Ping-Huei
    Chiang, Shih-Wei
    Chou, Ming-Chung
    Peng, Giia-Sheun
    Huang, Guo-Shu
    Hsu, Hsian-He
    Chen, Cheng-Yu
    贡献者: 醫學影像暨放射科學系
    日期: 2015-08-17
    上传时间: 2020-08-06T07:13:28Z (UTC)
    出版者: Medicine (Baltimore)
    ISSN: 0025-7974
    摘要: Abstract: The effect of intracranial internal carotid artery (ICA)
    calcification on cognitive impairment is uncertain. Our objective was
    to investigate whether intracranial ICA calcification is a significant
    cognitive predictor for cognitive impairment. Global cognition and
    degrees of intracranial ICA calcification of 579 subjects were assessed
    with Mini-Mental State Examination (MMSE) and Agatston calcium
    scoring method, respectively. Other risk factors for cognitive impairment, including age, education level, hypertension, diabetes mellitus,
    smoking, hyperlipidemia, and body mass index, were documented and
    analyzed for their associations with cognitive function.
    In univariate analyses, older age, lower education level, hypertension,
    diabetes mellitus, and higher intracranial ICA Agatston scores were significantly associated with cognitive impairment. In ordinal logistic regression,
    only age and total intracranial ICA Agatston score were significant risk
    factors for cognitive impairment. After adjustment for the other documented
    risk factors, subjects were 7% (95% CI: 5–10; P< 0.001) and 6% (95% CI:
    0–13; P¼ 0.04) more likely to have lower cognitive category with every
    year increment of age and every 100-point increment of the total intracranial
    ICA Agatston score respectively. These results suggest an important role of
    the intracranial ICA calcification on cognitive impairment.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/21014
    關聯: Medicine (Baltimore) . 2015 Sep;94(39):e1546.
    显示于类别:[醫學影像暨放射科學系暨碩士班] 期刊論文

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