Loading...
|
Please use this identifier to cite or link to this item:
https://ir.csmu.edu.tw:8080/ir/handle/310902500/19295
|
| Title: | Cytomegalovirus disease after liver transplantation: a nationwide population-based study |
| Authors: | PY, Liu
SB, Cheng
CC, Lin
CH, Lin
SN, Chang
CY, Cheng
ZY, Shi
KC, Tung
MJ, Wu |
| Contributors: | 中山醫學大學 |
| Date: | 2014-04 |
| Issue Date: | 2018-06-22T05:09:38Z (UTC)
|
| Publisher: | Transplant Proc |
| ISSN: | 0041-1345 |
| Abstract: | BACKGROUND:
Cytomegalovirus (CMV) disease is a significant complication after liver transplantation. The estimated incidence varies among studies, which have been conducted in single regional centers and with small cohorts. In this study, we investigated the occurrence of CMV disease among liver transplant recipients in a national cohort in Taiwan.
METHODS:
This retrospective study used data from the Taiwan National Health Insurance Research Database. All liver transplant recipients in the catastrophic illness database from 2000 to 2009 were enrolled. Cases of CMV disease were identified from the admission database with the use of the ICD-9-CM code 078.
RESULTS:
The national cohort consisted of 1,721 liver transplant recipients (1,200 men and 521 women) with a mean age of 43.9 ± 8.9 years at the time of transplantation. The mean follow-up duration was 3.6 ± 2.7 years. The mortality rate was 14.9% at 1 year and 20.5% at 5 years. During the study period, 84 patients (4.9%) were diagnosed with CMV disease. The overall prevalence of CMV disease was 14.5 per 100 person-years. The cumulative incidences of post-transplantation CMV infection at 3 months, 6 months, 1 year, 2 years, 5 years, and 10 years were 1.2%, 2.7%, 3.8%, 4.2%, 4.8%, and 4.9%, respectively. The most common CMV-related diseases were colitis, hepatitis, and pneumonia.
CONCLUSIONS:
The risk of CMV disease was significantly elevated in the first 6 months after liver transplantation in the Taiwanese cohort. |
| URI: | http://dx.doi.org/10.1016/j.transproceed.2013.12.009
https://ir.csmu.edu.tw:8080/ir/handle/310902500/19295 |
| Relation: | Transplant Proc. 2014 Apr;46(3):832-4 |
| Appears in Collections: | [醫學系] 期刊論文
|
Files in This Item:
| File |
Description |
Size | Format | |
|---|
| index.html | | 0Kb | HTML | 216 | View/Open |
|
All items in CSMUIR are protected by copyright, with all rights reserved.
|
