Lactate dehydrogenase leakage of hepatocytes with AH26 and AH plus sealer treatments

中山醫學大學機構典藏 CSMUIR > 口腔醫學院 > 牙醫學系暨碩士班 > 期刊論文 > Item 310902500/18293

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/18293

Title:	Lactate dehydrogenase leakage of hepatocytes with AH26 and AH plus sealer treatments
Authors:	Huang, T.-H.;Lii, C.-K.;Chou, M.-Y.;Kao, C.-T.
Date:	2000
Issue Date:	2017-08-09T04:45:10Z (UTC)
ISSN:	0099-2399
Abstract:	Numerous root canals filling materials are available in the field of dentistry, based on various formulas that contain a variety of different and partly mutagenic components, such as epoxy resin sealers, Ca(OH) 2-based materials, and zinc oxide-eugenol cements. AH Plus root canal sealer will not release formaldehyde according to the manufacturer, although AH26 does. The purpose of this study was to analyze the leakage of lactate dehydrogenase (LDH) from rat hepatocytes after treatment with AH26 and AH Plus root canal sealers in vitro. Hepatocytes from male Sprague-Dawley rats were used to test the cytotoxicity of AH26 and AH Plus. The root canal sealers were mixed and then dissolved in the dimethyl sulfoxide to final concentrations of 0.01%, 0.04%, and 0.1% (wt/vol), with a dimethyl sulfoxide concentration of <0.05%. Dosage-dependent and time-dependent lactate dehydrogenase leakage values were measured and tested by one-way ANOVA. The results showed that both AH26 and AH Plus are toxic to rat hepatocytes. At a low concentration, AH26 had a higher toxicity than AH Plus to rat hepatocytes. Copyright © 2000 by The American Association of Endodontists.
URI:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034277684&partnerID=40&md5=3358407cf970d540c0c83ebe53b66a74 https://ir.csmu.edu.tw:8080/ir/handle/310902500/18293
Relation:	Journal of Endodontics 26(9) ,509-511
Appears in Collections:	[牙醫學系暨碩士班] 期刊論文

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