What if a tumor is significantly enlarged just before stereotactic body radiation therapy? A case report and review of the literature

doi:10.1111/1759-7714.12405

中山醫學大學機構典藏 CSMUIR > 醫學院 > 醫學系 > 期刊論文 > Item 310902500/18173

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/18173

Title:	What if a tumor is significantly enlarged just before stereotactic body radiation therapy? A case report and review of the literature
Authors:	Chen, H.-J.;Liang, J.-A.;Chen, Chen C.-Y.;Yu, Yu Y.-H.;Chien, Chien C.-R.
Keywords:	Image-guidance radiotherapy;lung cancer;stereotactic body radiation therapy
Date:	2017
Issue Date:	2017-08-08T09:48:31Z (UTC)
Publisher:	John Wiley and Sons Inc.
ISSN:	17597706
Abstract:	Stereotactic body radiation therapy (SBRT) plays an important role in early stage non-small cell lung cancer. Tumor growth before radiotherapy planning (RTP) or during SBRT has been reported in lung cancer patients; however, little is known of growth during the period in-between (i.e. after RTP but before SBRT). An 83-year-old man referred to our hospital and diagnosed with medically inoperable non-small cell lung cancer was noted to have significant tumor progression on day 1 of cone beam computed tomography just before the planned SBRT delivery. Because of uncertainty of the underlying etiology and unfamiliarity with this phenomenon, we made a clinical decision to arrange re-simulation and revise our treatment to conventional fractionated radiotherapy (CFRT). After an initial response, distant metastases occurred eight months after CFRT. The patient received best supportive care and was under hospice care at the last follow-up (27 months after CFRT). We report a case with significant tumor growth just before planned SBRT. Optimal management in this scenario requires further investigation. © 2016 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd
URI:	http://dx.doi.org/10.1111/1759-7714.12405 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85002977640&doi=10.1111%2f1759-7714.12405&partnerID=40&md5=04b1c2006570769c3e5f8565f056ee82 https://ir.csmu.edu.tw:8080/ir/handle/310902500/18173
Relation:	Thoracic Cancer 8(2) ,118-120
Appears in Collections:	[醫學系] 期刊論文

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