中山醫學大學機構典藏 CSMUIR:Item 310902500/18148
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    题名: Predictability of early onset atopic dermatitis by cord blood IgE and parental history
    作者: Chang, W.-T.;Sun, H.-L.;Lue, K.-H.;Chou, M.-C.
    关键词: Atopic dermatitis;Cord blood;IgE;Parental history
    日期: 2005
    上传时间: 2017-08-07T09:14:50Z (UTC)
    ISSN: 16088115
    摘要: Cord blood IgE and atopic family history have been used as predictors of atopic disease in infants for more than 20 years. In recent years, the value of cord blood IgE in predicting the development of atopic dermatitis has been questioned, while family history of atopy has consistently been regarded as a useful predictor for atopic dermatitis. A birth cohort was followed-up to 6 months of age to record the development of atopic dermatitis and to study its association with cord blood IgE levels and parental history of atopy. The cumulative incidence of atopic dermatitis over the 1st, 3rd and 6th months of life amounted to 5.0%, 8.2% and 14.0%, respectively. When the cutoff value for cord blood IgE was set at 0.5 kU/L, there was a significant association between elevated cord blood IgE level and atopic dermatitis at 1, 3 and 6 months of age; when the cutoff value was set at 0.9 kU/L, the association was only found at 3 months of age. There was a significant association with atopic history of the mother. The effect of maternal atopic history on atopic dermatitis seen only at 1 month was lost by 3 months of age. There was no correlation between paternal history and atopic dermatitis. In our study, the predictive capacity of maternal history and cord blood IgE was not high enough to recommend them as screening factors.
    URI: http://dx.doi.org/
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-33644951000&partnerID=40&md5=3716d807905d8d331437ab1383a069e5
    https://ir.csmu.edu.tw:8080/ir/handle/310902500/18148
    關聯: Acta Paediatrica Taiwanica 46(5),272-277+329
    显示于类别:[醫學系] 期刊論文

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