中山醫學大學機構典藏 CSMUIR:Item 310902500/17881
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    题名: The clinical management of cesarean section-acquired Mycobacterium abscessus surgical site infections
    作者: Tsao, Shih-Ming
    Liu, Keh-Sen
    Liao, Hsien-Hua
    Huang, Tian-Lin
    Shen, Gwan-Han
    Tsao, Thomas Chang-Yao
    Lee, Yuan-Ti
    贡献者: 中山醫學大學
    日期: 2014
    上传时间: 2017-06-29T09:41:19Z (UTC)
    ISSN: 2036-6590
    摘要: Abstract
    INTRODUCTION:
    Rapidly growing mycobacteria (RGM) can cause a broad spectrum of both community and healthcare-associated infections in humans. The aim of this study was to report the clinical management and outcomes of successive patients following cesarean delivery with healthcare-associated surgical site infections (SSIs) caused by RGM.
    METHODOLOGY:
    Patients who were admitted to Chung Shan Medical University Hospital, Taichung, Taiwan, between September 2006 and July 2008, and who developed SSIs following cesarean delivery at an obstetrics hospital and were then referred to our hospital, were enrolled. Demographic characteristics of the patients and clinical isolates were obtained retrospectively and an environmental investigation was performed. PCR-restriction fragment length polymorphism (PCR-RFLP) analysis of the hsp65gene and pulsed-field gel electrophoresis (PFGE) of large genomic DNA restriction fragments were applied to differentiate Mycobacterium species.
    RESULTS:
    Seventeen patients were diagnosed with RGM infections by microbiology and/or histopathology. Mycobacterial isolates by PCR-RFLP analysis from 15 patients revealed Mycobacterium abscessus (M. abscessus) and M. lentiflavum. Most of the patients received surgical debridement and combination antimicrobial therapy and were eventually cured.
    CONCLUSIONS:
    Our study demonstrates the potential that RGM infections have in causing healthcare-associated SSIs. Surgery plus prolonged combination antimicrobial therapy seemed to be an effective option for the management of M. abscessus infections.
    URI: https://doi.org/10.3855/jidc.3821
    https://ir.csmu.edu.tw:8080/ir/handle/310902500/17881
    關聯: J Infect Dev Ctries. 2014 Feb 13;8(2):184-92.
    显示于类别:[醫學系] 期刊論文

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