中山醫學大學機構典藏 CSMUIR:Item 310902500/17878
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 17905/22920 (78%)
造訪人次 : 7552767      線上人數 : 437
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋


    請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/17878


    題名: Effectiveness of the BDProbeTec ET system for detection of Mycobacterium tuberculosis complex in sputum and bronchoalveolar lavage specimens
    作者: HC, Hung
    CH, Chan
    SM, Tsao
    SC, Chen
    TC, Wu
    MC, Lu
    DJ, Wu
    SJ, Huang
    YT, Lee
    貢獻者: 中山醫學大學
    關鍵詞: Bronchoalveolar lavage;Mycobacterium tuberculosis;Acid-fast bacilli staining;Molecular diagnosis;BDProbeTEC ET system
    日期: 2012
    上傳時間: 2017-06-29T09:32:06Z (UTC)
    出版者: The Brazilian Journal of Infectious Diseases
    ISSN: 1413-8670
    摘要: Abstract
    Objective

    The diagnostic efficacy of the BDProbeTEC ET Mycobacterium tuberculosis (MTB) complex direct detection assay (DTB) performed on bronchoalveolar lavage (BAL) specimens and sputum smears was compared with acid-fast bacilli (AFB) smear microscopy.
    Method

    AFB smear microscopy, DTB and culture results of 286 patients with pulmonary tuberculosis were retrospectively reviewed. A total of 120 patients provided expectorated sputum samples, and 166 patients provided BAL specimens. Culture results and clinical diagnosis were used as gold standards.

    Results

    The sensitivity and specificity of the DTB assay in detecting MTB in sputum specimens was significantly higher compared to AFB smear microscopy (83.7% and 82.4%, vs. 75.6%, and 41.2%, respectively). The sensitivity and specificity of the DTB assay in detecting MTB in sputum samples was 77.2% and 100% compared to clinical diagnosis, while AFB smear had a sensitivity and specificity of 70.3% and 26.3%, respectively. Compared to culture, DTB had a sensitivity and specificity of 82.8% and 93.2%, respectively, in detecting MTB from BAL specimens; AFB smear had a sensitivity and specificity of 41.9% and 87.7%, respectively. Compared to clinical diagnosis, DTB had a sensitivity and specificity of 67.2% and 100%, respectively, in detecting MTB from BAL specimens; AFB smear had a sensitivity and specificity of 34.8% and 79.5%, respectively.

    Conclusions

    The superior performance of the DTB assay relative to AFB smear microscopy makes it a valuable tool to enable early diagnosis of MTB, thereby improving patient care and reducing transmission.
    URI: https://doi.org/10.1016/S1413-8670(12)70318-5
    https://ir.csmu.edu.tw:8080/ir/handle/310902500/17878
    關聯: The Brazilian Journal of Infectious Diseases Volume 16, Issue 3, May–June 2012, Pages 242-249
    顯示於類別:[醫學系] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    index.html0KbHTML306檢視/開啟


    檢視Licence

    SFX Query

    在CSMUIR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋