習慣性打鼾成人聽力損傷的危險因子探討

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題名:	習慣性打鼾成人聽力損傷的危險因子探討 Risk factors for hearing impairment in habitual snorers
作者:	曹傑漢 Tsao, Chien-Han
貢獻者:	中山醫學大學:醫學研究所;李孟智
關鍵詞:	打鼾;聽力損失;糖尿病;夜間多頻道生理檢查儀;睡眠呼吸中止症 Snoring;hearing loss;hypertension;diabetes mellitus. nocturnal polysomnography, obstructive sleep apnea syndrome
日期:	2016
上傳時間:	2017-01-18T04:43:54Z (UTC)
摘要:	背景:研究打鼾患者的聽力表現並導致聽力損失的相關因子。方法:自2007年10月自2008年10月，收集中山醫學大學附設醫院耳鼻喉科162名以打鼾為主訴之成成年人(平均年齡45.4±13.3歲) 收集變項含人口學數據，罹患心血管疾病、高血壓、高血脂、糖尿病等共病項目與目前或過去有否抽煙或飲酒習慣。安排夜間多頻道生理檢查儀診斷是否罹患睡眠呼吸中止症。聽損的定義是，500, 1k, 2k, 4k Hz,的聽力閥質大於25分貝。低/中頻聽損的定義是左右任一耳在500, 1k, and 2k Hz的聽閥平均大於25 分貝；高頻聽損的定義是左右任一耳在4k, 6k, and 8k Hz 的聽閥平均大於25分貝。使用邏輯式回歸模式來分析造成聽力損失的因子。結果:19%打鼾者呈現雙耳聽損，30%的患者呈現至少一耳的聽損。在校正性別，菸，酒暴露史後，多便術分析的結果顯示；年齡，高血壓與低/中頻，高頻聽損有相關且不論是單耳或雙耳。而糖尿病與單耳或雙耳的低/中頻聽損有相關。結論:我們認為年齡、高血壓、第二型糖尿病可以影響打鼾者的聽覺。年齡與高血壓影響所有頻率的聽覺，第二型糖尿病則對低/中頻聽覺的敏感性造成影響。 Background: We investigated hearing performance in snorers to identify risk factors for hearing loss (HL). Methods: We enrolled 162 subjects aged ≥ 18 years (mean = 45.4 ± 13.3 years) Withcomplaints of habitual snoring from our outpatient clinic at the Chung Shan Medical University Hospital, between October 2007 and October 2008. Demographic and anthropometric data, coexisting diseases, smoking and drinking status were recorded. Nocturnal polysomnography was arranged for diagnosis of obstructive sleep apnea syndrome.HLwas defined as the average of pure tone thresholds measured at 500, 1k, 2k, and 4k Hz > 25dB. Low/mid-frequency HL was defined as the average of pure tone threshold measured at500, 1k, and 2k Hz > 25 dB; high-frequency HL was defined as the average of pure tonethresholds measured at 4k, 6k, and 8k Hz >25 dB. Logistic regression was used to determinerisk factors for HL. Results: Nineteen percent of snorers had HL in a better ear (bilateral impairment) and 30%had HL in a worse ear (at least one-sided impairment). After adjusting for sex, smoking, andalcohol consumption, multivariate analysis showed that age (p< 0.05) and hypertension (p<0.05) were significantly associated with low/mid- and high-frequency HL in either the worseor the better ear; type 2 diabetes (p< 0.05) was only related to low/mid-frequency HL ineither the worse or the better ear. Conclusions: Our results suggest that age, hypertension, and type 2 diabetes can affect hearing acuity among snorers; age and hypertension affect all-frequency HL, while type 2 diabetes affects low/mid-frequency hearing acuity.
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/16289
顯示於類別:	[醫學研究所] 博碩士論文

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