中山醫學大學機構典藏 CSMUIR:Item 310902500/15847
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    题名: Effect of cholestin on toxicity of vitamin A in rats.
    作者: YH, Yeh
    YT, Lee
    YL, Hsieh
    贡献者: 中山醫學大學
    关键词: Cholestin;Hepatotoxicity;Nephrotoxicity;Toxicity;Vitamin A
    日期: 2011
    上传时间: 2016-08-16T04:23:04Z (UTC)
    ISSN: 0308-8146
    摘要: A study was undertaken to investigate the effect of cholestin on the toxicity of vitamin A in male wistar rats. The rats were divided into six groups and fed different diets with or without supplement of 1% cholestin and 25,000-50,000 (IU) vitamin A for 2 months. Hence, the symptoms of vitamin A toxicity in rats included loss of body weight, hepatotoxicity and nephrotoxicity. However, these toxic effects of vitamin A were significantly reduced when the rats fed a diet supplemented with cholestin. Furthermore, the level of vitamin A in the serum of rats treated with cholestin and vitamin A was higher than that of the rats treated with vitamin A alone. It indicated that cholestin might play a role in reducing the toxic effect of vitamin A in rats.
    URI: http://dx.doi.org/10.1016/j.foodchem.2011.10.082
    https://ir.csmu.edu.tw:8080/ir/handle/310902500/15847
    關聯: Food Chemistry Volume 132, Issue 1, 1 May 2012, Pages 311–318
    显示于类别:[健康餐飲暨產業管理學系暨碩士班] 期刊論文

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