Surface nanoporosity of β-type Ti–25Nb–25Zr alloy for the enhancement of protein adsorption and cell response

doi:10.1016/j.surfcoat.2014.02.037

中山醫學大學機構典藏 CSMUIR > 口腔醫學院 > 口腔醫學研究所 > 期刊論文 > Item 310902500/15806

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/15806

Title:	Surface nanoporosity of β-type Ti–25Nb–25Zr alloy for the enhancement of protein adsorption and cell response
Authors:	Huang, Her-Hsiung Wu, Chia-Ping Sun, Ying-Sui Yang, Wei-En Lin, Mau-Chin Lee, Tzu-Hsin
Contributors:	中山醫大口腔科學研究所
Keywords:	Ti–25Nb–25Zr alloy;Electrochemical anodization;Surface nanoporosity;Protein adsorption;Cell response
Date:	2014
Issue Date:	2016-08-15T06:11:17Z (UTC)
ISSN:	0257-8972
Abstract:	This paper outlines a simple method for the electrochemical anodization of β-type Ti–25Nb–25Zr (Ti25Nb25Zr) alloy with a low elastic modulus (approximately 70 GPa) to alter its surface topography for bone implant applications. Surface characteristics including topography, roughness, hydrophilicity, and protein adsorption (fibronectin and albumin) were investigated. Human bone marrow mesenchymal stem cell responses, including adhesion, migration, proliferation, and mineralization, were also evaluated. The experimental results demonstrate that the electrochemical anodization process produced a nanoporous surface (pore size < 15 nm) on Ti25Nb25Zr alloy. This surface nanotopography did not alter the surface roughness or hydrophilicity of the Ti25Nb25Zr alloy but was capable of enhancing biological responses, including protein adsorption, cell adhesion, cell migration, cell proliferation, and cell mineralization. The created surface nanoporosity on β-type Ti25Nb25Zr alloy has a high potential for bone implant applications.
URI:	http://dx.doi.org/10.1016/j.surfcoat.2014.02.037 https://ir.csmu.edu.tw:8080/ir/handle/310902500/15806
Relation:	Surface and Coatings TechnologyVolume 259, Part B, 25 November 2014, Pages 206–212
Appears in Collections:	[口腔醫學研究所] 期刊論文

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	403	View/Open

View Licence

Loading...