中山醫學大學機構典藏 CSMUIR:Item 310902500/15610
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    题名: Spatial short-term memory is impaired in dependent betel quid chewers
    作者: Chiu, M.-C.
    Shen, B.
    Li, S.-H.
    Ho, M.-C.
    贡献者: 醫學研究所
    关键词: Betel quid;Dependence;Short-term memory
    日期: 2016-08-01
    上传时间: 2016-08-04T03:42:46Z (UTC)
    出版者: Springer Verlag
    ISSN: 00333158
    摘要: Rational: Betel quid is regarded as a human carcinogen by the World Health Organization. It remains unknown whether chewing betel quid has a chronic effect on healthy betel quid chewers’ memory. Objectives: The present study aims to investigate whether chewing betel quid can affect short-term memory (STM). Methods: Three groups of participants (24 dependent chewers, 24 non-dependent chewers, and 24 non-chewers) were invited to carry out the matrix span task, the object span task, and the digit span task. All span tasks’ results were adopted to assess spatial STM, visual STM, and verbal STM, respectively. Besides, there are three set sizes (small, medium, and large) in each span task. Results: For the matrix span task, results showed that the dependent chewers had worse performances than the non-dependent chewers and the non-chewers at medium and large set sizes. For the object span task and digit span task, there were no differences in between groups. In each group, recognition performances were worse with the increasing set size and showing successful manipulation of memory load. Conclusions: The current study provided the first evidence that dependent betel quid chewing can selectively impair spatial STM rather than visual STM and verbal STM. Theoretical and practical implications of this result are discussed. © 2016, Springer-Verlag Berlin Heidelberg.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/15610
    http://dx.doi.org/10.1007/s00213-016-4331-9
    關聯: Psychopharmacology Volume 233, Issue 15-16, 1 August 2016, Pages 2925-2932
    显示于类别:[醫學研究所] 期刊論文

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