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Please use this identifier to cite or link to this item:
https://ir.csmu.edu.tw:8080/ir/handle/310902500/15604
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| Title: | Chronic obstructive pulmonary disease and anxiety disorders: A nationwide population-based study in Taiwan |
| Authors: | Hsieh, M.-H.
Lee, C.T.-C.
Tsai, P.-J.
Tsai, C.-J.
Liao, Y.-T.
Chen, V.C.-H.
Stewart, R. |
| Contributors: | 醫學研究所 |
| Keywords: | Anxiety;Charlson comorbidity index;Chronic obstructive pulmonary disease;Prednisone |
| Date: | 2016-09-01 |
| Issue Date: | 2016-08-04T03:20:27Z (UTC)
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| Publisher: | Elsevier Inc. |
| ISSN: | 01638343 |
| Abstract: | Objective: Few studies have investigated the relationship between chronic obstructive pulmonary disease (COPD) and anxiety disorder outcomes. We sought to investigate the association in a large national sample. Methods: Cases were identified from Taiwan's National Health Insurance Research Database who were aged 15 years and above, with a new primary diagnosis of COPD (International Classification of Diseases, Ninth Revision codes: 491, 492, 494 and 496) between 2000 and 2007. The 29,951 cases identified were compared to 29,951 controls matched on sex, age, urban/rural residence and socioeconomic status based on insurance premium. Both groups were followed until the end of 2008 for instances of anxiety disorders. Competing risk-adjusted Cox regression analyses were applied, adjusting for matching variables, Charlson comorbidity index, hospital admission days and daily dose of prednisone. Results: Of the 59,902 subjects, 3951 were found to have anxiety disorders during a mean (SD) follow-up period of 5.5 (2.5) years. COPD, female, urban residence, lower dose of prednisone use, depressive disorders and higher outpatient visits were independent predictors of incident anxiety disorder. Conclusions: COPD was associated with increased risk of an anxiety disorder diagnosis, independent of a number of potential confounding factors. © 2016 Elsevier Inc. |
| URI: | https://ir.csmu.edu.tw:8080/ir/handle/310902500/15604 |
| Relation: | General Hospital Psychiatry Volume 42, 1 September 2016, Pages 1- |
| Appears in Collections: | [醫學研究所] 期刊論文
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