中山醫學大學機構典藏 CSMUIR:Item 310902500/11874
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/11874


    题名: First identification of methicillin-resistant Staphylococcus aureus
    作者: Lee YT;Lin DB;Wang WY;Tsao SM;Yu SF;Wei MJ;Yang SF;Lu MC;Chiou HL;Chen SC;Lee MC
    贡献者: 中山醫學大學
    关键词: MLST;Methicillin-resistant Staphylococcus aureus (MRSA);Multiplex PCR;Nosocomial transmission;Outbreak;PFGE
    日期: 2011-06
    上传时间: 2015-07-30T10:19:57Z (UTC)
    ISSN: 0732-8893
    摘要: We used molecular typing methods to investigate an outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infections in a respiratory care ward in Taiwan. From March to June 2006, the incidence of MRSA infection increased 3.75-fold. The overall carrier rates among the health care workers (HCWs) were 31.3% (total S. aureus), 16.4% (MRSA), and 14.9% (methicillin-sensitive SA, MSSA). Pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), antibiograms derived from susceptibility testing of MRSA isolates, and multiplex polymerase chain reaction (PCR) provided strong epidemiologic and microbiologic evidence that the outbreak of MRSA infections at our hospital was linked to the same PFGE pulsotype A SCCmec type II, pvl-negative, MLST ST5 strain of MRSA isolated from seven HCWs and five patients. The outbreak was controlled by application of topical fucidin ointment to the anterior nares in all colonized HCWs. Multiplex PCR combined with PFGE and MLST is a feasible method for outbreak investigations in routine clinical laboratories.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/11874
    http://dx.doi.org/10.1016/j.diagmicrobio.2010.12.021
    關聯: Diagn Microbiol Infect Dis. 2011 Jun;70(2):175-82
    显示于类别:[醫學檢驗暨生物技術學系暨碩士班] 期刊論文

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