Pediatric reference intervals for several biochemical analytes in school children in Central Taiwan.

doi:10.1016/S0929-6646(10)60009-5

中山醫學大學機構典藏 CSMUIR > 醫學科技學院 > 醫學檢驗暨生物技術學系暨碩士班 > 期刊論文 > Item 310902500/11808

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/11808

Title:	Pediatric reference intervals for several biochemical analytes in school children in Central Taiwan.
Authors:	Lai, DS Chen, SC Chang, YH Chen, CY Lin, JB Lin, YJ Yang, SF Yang, CC Chen, WK Lin, DB
Contributors:	中山醫學大學
Date:	2009
Issue Date:	2015-07-29T09:21:07Z (UTC)
ISSN:	0929-6646
Abstract:	BACKGROUND/PURPOSE: Reference intervals of biochemical tests for screening for diabetes mellitus and liver and renal function among school children in Central Taiwan have never been documented. Therefore, this study aimed to establish the reference intervals for the above mentioned biochemical tests for pediatric populations. METHODS: A total of 4326 subjects, including 2029 kindergarten children, 1624 elementary-school children, 325 junior-high-school children, and 348 teachers were selected randomly in Central Taiwan. All serum alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine (Cr) and glucose levels were determined using a Beckman Synchron CX5 analyzer. The reference intervals reflected estimates of the 2.5th-97.5th percentiles of non-parametric distributions. RESULTS: Adults had significantly higher biochemical analyte values [except for BUN/creatinine (B/C) ratio] than children had. Multiple logistic regression analysis showed that biochemical analyte values were significantly higher in male than in female subjects. The concentrations of glucose and Cr increased with age. On the contrary, the B/C ratio decreased with age. CONCLUSION: Our study provides new pediatric reference intervals (2.5th-97.5th percentiles) of 60-99 mg/dL for serum glucose concentrations, 8-38 IU/L for ALT, 0.4-1.1 mg/L for Cr, 8.7-18.0 mg/L for BUN, and 10-34 for B/C ratio. The B/C ratio in children was higher than those of adults, possibly due to that children had a higher intake of protein. PMID: 20040461 [PubMed - indexed for MEDLINE]
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/11808 http://dx.doi.org/10.1016/S0929-6646(10)60009-5
Relation:	J Formos Med Assoc. 2009 Dec;108(12):957-63.
Appears in Collections:	[醫學檢驗暨生物技術學系暨碩士班] 期刊論文

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