Change in protein kinase C activity on day 5 of decidualization in pseudopregnant rats.

中山醫學大學機構典藏 CSMUIR > 醫學院 > 生化微生物免疫研究所 > 期刊論文 > Item 310902500/11554

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题名:	Change in protein kinase C activity on day 5 of decidualization in pseudopregnant rats.
作者:	Shyu, JC Hsieh, YS Chang, CL Tsai, CC Cheng, CK Liu, JY
贡献者:	中山醫學大學
日期:	1997
上传时间:	2015-07-22T09:05:56Z (UTC)
摘要:	The specific activities of protein kinase C (PKC) and protein tyrosine kinase (PTK) were determined in the decidualized uterine tissue of pseudopregnant rat on day 5 of decidualization. We found that the activity of the cytosolic PKC was significantly lower in decidualized uterine tissue as compared with that of the controlateral untreated uterine tissues (1.5 +/- 1.4 versus 57.5 +/- 4.1 pmol 32P/min/mg, P < 0.001), while the PKC activity in particulate fraction was not significantly different (124.8 +/- 14.5 versus 236.8 +/- 88.6 pmol 32P/min/mg) concerning protein concentration. The reduced expression of the cytosolic PKC activity was observed on all five individual rats. In contrast, the decidualized uterine tissue showed similar cytosolic PTK activity as compared with the controlateral untreated uterine tissues (20.1 +/- 3.0 versus 20.6 +/- 3.2 pmol 32P/min/mg protein), and similar in particulate PTK activity (42.5 +/- 9.0 versus 36.8 +/- 5.1 pmol 32P/min/g protein). These results indicate that cytosolic PKC activity may be involved in modulation of decidual growth.
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/11554
關聯:	Chin J Physiol. 1997 Jun 30;40(2):107-12.
显示于类别:	[生化微生物免疫研究所] 期刊論文

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