Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.

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题名:	Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.
作者:	Kuo, WH Yang, SF Chu, SC Lu, SO Chou, FP Hsieh, YS
贡献者:	中山醫學大學
关键词:	Metalloproteinase;Metastasis;Tissue preference
日期:	2003
上传时间:	2015-07-22T07:59:17Z (UTC)
ISSN:	0304-3835
摘要:	This study was designed to investigate the changes of matrix metalloproteinase (MMP)-2 and MMP-9 in host tissues in response to the growth of tumor cells. Zymogram showed that the responses of both MMPs in the host tissues were differential but concurrent. The liver, a prime target of metastases, had profound increases in MMP-2 and -9. The other usual targets had significant increases in MMP-9. MMP-2 was specifically increased in the spleen. These results indicate that the growth of tumor cells at the primary site could influence the MMP system of host tissues located at the distance.
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/11541 http://dx.doi.org/10.1016/S0304-3835(02)00323-3
關聯:	Cancer Lett. 2003 Jan 10;189(1):103-12.
显示于类别:	[生化微生物免疫研究所] 期刊論文

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