中山醫學大學機構典藏 CSMUIR:Item 310902500/11298
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    题名: Clinical application of platelet-rich fibrin as the sole grafting material in periodontal intrabony defects
    作者: Chang, Yu-Chao
    Wu, Kuo-Chin
    Zhao, Jiing-Huei
    贡献者: 中山醫學大學
    关键词: periodontal intrabony defects;periodontitis;platelet-rich fibrin;regeneration
    日期: 2011
    上传时间: 2015-07-15T08:40:55Z (UTC)
    ISSN: 1991-7902
    摘要: Background/purpose

    Platelet-rich fibrin (PRF) obtained by Choukroun’s technique is a healing biomaterial that concentrates in a single autologous fibrin membrane, mostly of platelets and cytokines from blood harvest, and without any artificial biochemical modification. However, no data are presently available concerning the use of PRF for the treatment of periodontal intrabony defects. This report was to present the clinical and radiographic changes of a patient with periodontal intrabony defects treated with PRF.

    Material and methods

    The left mandibular first molar (#36) and left maxillary second molar (#27) with intrabony defects were filled with PRF as the sole grafting material in a 38-year-old female patient. The primary outcomes evaluated in this study included changes in probing depth, attachment level, and radiographic bone density between baseline and 6 months postoperatively.

    Results

    The results showed that the application of PRF as the sole grafting material in intrabony defects exhibited pocket reduction and gain in clinical attachment after 3 months and 6 months. Using National institute of health program, the 6 months postoperative radiographic density of images for #27 and #36 showed an increase of 1.6 and 1.3 fold compared with each preoperative radiography, respectively.

    Conclusions

    From a clinical and radiologic point of view at 6 months after surgery, the use of PRF as the sole grafting material seems to be an effective modality of regenerative treatment for periodontal intrabony defects.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/11298
    http://dx.doi.org/10.1016/j.jds.2011.05.010
    關聯: Journal of Dental Sciences Volume 6, Issue 3, September 2011, Pages 181–188
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