中山醫學大學機構典藏 CSMUIR:Item 310902500/11160
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    题名: Tissue and cell reactions to implanted root-end filling materials
    作者: Kao, Chia-Tze
    Tsai, Chung-Hung
    Huang, Tsui-Hsien
    贡献者: 中山醫學大學
    日期: 2006
    上传时间: 2015-07-10T10:34:47Z (UTC)
    ISSN: 0957-4530
    摘要: The use of root-end filling materials designed to stimulate hard and soft tissue repair in periradicular tissues is highly recommended. The materials should demonstrate good cell and tissue compatibility. The aim of the present study was to compare in vitro biocompatibility and in vivo tissue reaction with calcium hydroxide-based, eugenol-based and mineral trioxide aggregate root-end filling materials. The human osteosarcoma cell line was treated with immersed root end filling materials. The test materials were implanted in rats and the results observed at 6 and 8 weeks. In vitro, the highest survival rate was demonstrated for the mineral trioxide aggregate (p<0.05). In vivo, a radiopaque ring was evident in the calcium hydroxide implants on the eight-week radiograph. Histopathology revealed eugenol-based material with the inflammatory cells around the implant, with fibrous connective tissue forming around the calcium hydroxide-based analog. The mineral trioxide aggregate appears to be well tolerated by the tissue.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/11160
    http://dx.doi.org/10.1007/s10856-006-9844-z
    關聯: Journal of Materials Science: Materials in Medicine September 2006, Volume 17, Issue 9, pp 841-847
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