Neurological images and the predictors for neurological sequelae of epidemic herpangina/hand-foot-mouth disease with encephalomyelitis.

doi:10.1055/s-0033-1360480

中山醫學大學機構典藏 CSMUIR > 醫學院 > 醫學系 > 期刊論文 > Item 310902500/10455

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题名:	Neurological images and the predictors for neurological sequelae of epidemic herpangina/hand-foot-mouth disease with encephalomyelitis.
作者:	Tsai JD Kuo HT Chen SM Lue KH Sheu JN
贡献者:	中山醫學大學
关键词:	enterovirus 71;neurological images;predictors;neurological sequelae;Taiwan
日期:	2014-04
上传时间:	2015-03-16T04:11:14Z (UTC)
ISSN:	0174-304X
摘要:	Since 1998 in Taiwan, enterovirus (EV) 71 epidemics have caused encephalomyelitis and placed a significant burden on parents and physicians. In this study, we present clinical manifestations, magnetic resonance (MR) imaging findings, and neurological sequelae on epidemic EV-infected patients with encephalomyelitis. Of the 46 patients, 14 patients presented with neurological sequelae; of them, 3 patients suffered from complications of mental regression. Predictors of unfavorable neurological sequelae were myoclonic jerks (> 4 times/night) and pleocytosis (167/μL) of the cerebrospinal fluid (CSF). Results from viral culture and MR imaging indicated that positive identification of EV71 infection was associated significantly with lesions on MR imaging. Our results show that hand-foot-mouth disease carries a higher risk of encephalomyelitis and that frequent myoclonic jerks and pleocytosis of the CSF are risk factors for subsequent neurological sequelae. Positive identification of EV71 might be useful as a predictor of lesions in MR imaging.
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/10455 http://dx.doi.org/10.1055/s-0033-1360480
關聯:	Neuropediatrics. 2014 Apr;45(2):102-8
显示于类别:	[醫學系] 期刊論文

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