低強度經顱直流電刺激(transcranial direct current stimulation, tDCS)是一種安全、非 侵入性的科學工具，具有即時與長期效果可調節大腦皮質細胞的興奮性，經顱直流電 刺激的發展受到科學界日益重視。本兩年期研究計畫擬利用經顱直流電刺激活化大腦 運動區，從握力特徵、變異性與肌肉運動單元行為(motor unit behavior)的改變，探討經 顱電刺激對於中樞性肌肉疲勞的緩減效益。第一年計畫探討興奮性穿顱電刺激的電極 位置對肌肉疲勞恢復的效應，第二年計畫探討興奮性穿顱電刺激的即時效應對進行中 疲勞性收縮所產生的影響。本計畫預期可發現有效抑制疲勞產生的穿顱電刺激模式與 神經生理機制；本研究計劃有學理參考價值，同時，對提升運動耐力與競賽表現有潛 在的價值。 Low-intensity transcranial direct current stimulation (tDCS) is a safe non-invasive scientific tool for modulating excitability of cortical neurons with significant acute and after effects. The development of tDCS receives increasing attention of researchers in the related fields. This two-year proposal will use tDCS to ameliorating central effect on muscular fatigue, in light of changes in force characteristics, force variability properties, and motor unit behaviors. The project of the first year will investigate optimal electrode positioning for fatigue recovery with tDCS. The project of the second year will investigate immediate effect of tDCS on fatigue suppression during sustained contraction. The proposal is expected to gain insight into effective mode of tDCS to wane fatigue development and its underlying neurophysiological mechanisms. The results of the proposal have potential theoretical and practical benefits to gain endurance and performance for athletes by tDCS.
